Valle de Guadalupe is the key wine region in the state of Baja California, Mexico. Baja California, in turn, is responsible for 90 percent national wine production.

At the heart of the valley is Guadalupe village, which lies 14 miles (20km) north of Ensenada city. The valley runs northeast to southwest on either side of Guadalupe, stretching from the Pacific coast inland for roughly 20 miles (32 km). Over that distance the land ascends dramatically from the cliffs above Todos Santos Bay to several thousand feet above sea level.